THE TROPHOBLAST AND ITS RELATION TO CANCER
by Dr. Lawrence Wilson
© February 2021, LD Wilson Consultants, Inc.
All information in this article is for educational purposes only. It is not for the diagnosis, treatment, prescription or cure of any disease or health condition.
II. STIMULI FOR TROPHOBLAST FORMATION
III. REVERSAL AND HEALING
The trophoblast is a very unusual type of cell found in all animals. Perhaps there is an equivalent cell type in plants, as well. It arises during early pregnancy. The word trophoblast from the Latin language means to nourish the baby. This is the function of this tissue.
Of special interest is the fact that when this tissue arises outside of normal pregnancy, it is responsible for cancer formation. This is called the trophoblastic theory of cancer.
In 1902, John Beard, MD, a prominent embryologist, published a paper in The Lancet entitled The Trophoblastic Theory Of Cancer (Beard, J., 1902). The theory is quite simple and has never been disproven.
In fact, fairly recently it received strong confirmation by scientists at the University of Michigan, USA (Townsend Letter, #240, 2003). However, this is not taught to doctors, perhaps because if it were, cancer would cease to be as much of a threat to human health and some do not want this to occur.
Dr. Beard showed that a normal tissue of the body, the trophoblast, exhibits characteristics identical to cancer. It is invasive, metastatic, forms new blood vessels (angiogenesis) and has the same specific markers and chemical composition as cancer cells.
WHAT IS THE TROPHOBLAST?
The trophoblast is a cell type that is the outer part of a fertilized egg. It begins to grow very soon after conception and is essential for life.
The word tropho-blast means Ôto nourish the baby'. For example, trophology is another word for nutrition. A blast in medical jargon is an immature organism or baby. The trophoblast does the following:
Roles of the trophoblast.
- As the fertilized egg moves out of the fallopian tube and into the motherŐs uterus, the trophoblast reaches out tiny tentacles that grab on and hold on to the motherŐs uterine lining. This prevents the egg from just falling out of the motherŐs uterus and being lost. This phase of pregnancy is called implantation of the egg.
- The trophoblast then invades the lining of the uterus. It burrows deep into the motherŐs uterine lining.
- As it grows, it sends out tiny tubules that become blood vessels. Through these vessels, it is able to steal blood and nutrients from the mother and send them to the developing baby. Later, the placenta helps with this job, but for the first 8-12 weeks of pregnancy, only the trophoblast nourishes the baby.
- It also steals souls from the mother and sends them to the developing baby.
- The trophoblast also weakens the lining of the uterus in the area where the fertilized egg has implanted. This is necessary because a baby is a foreign object inside its mother. If the trophoblast did not weaken the tissue somewhat, the mother would reject the foreign object.
(Those who advocate abortion are wrong when they say that an unborn baby is part of its mother and therefore she should decide its fate. This is not true! The baby is always an independent being and never part of its mother.)
Choriocarcinoma. If the trophoblast overgrows, which is fortunately rare, the result is a very virulent form of cancer, choriocarcinoma. It usually kills both mother and fetus within a few weeks.
One may ask, if the trophoblast only develops during pregnancy, how can it explain all cancers, even those in men? Dr. Beard found that the stem cells, also called totipotent cells, that form the trophoblast are present all over the body in small numbers. Given the right stimulus, they develop into trophoblast. It appears that this is a mechanism to kill off sick bodies. A key to understanding cancer is to understand what makes these cells grow.
II. TROPHOBLAST STIMULI
One of the primary stimuli for the growth of the trophoblast is high estrogen, as occurs during pregnancy. Estrogen is associated with cell proliferation. Modern medicine acknowledges that estrogen is a potent carcinogen. This is why estrogen inhibitors are among the drugs used for cancer.
One may then ask, why does so much cancer occur in men, or in post-menopausal women who do not produce as much estrogens? The answer is that everyone's adrenal glands and perhaps other sites produce estrogens, in both sexes and at all ages.
Normal estrogen production by the adrenal glands or ovaries is not a problem. The liver converts potent estrogens such as estradiol and estrone into harmless chemicals and excretes them in the bile and urine.
However, when the liver is toxic or otherwise compromised, it cannot detoxify estrogens properly. Estrone, in particular, increases and the stage is set for cancer. Arthur GuytonŐs Textbook Of Physiology explains the fate of estrogens as follows:
ŇThe liver conjugates the estrogens É and about one-fifth of these conjugated products are excreted in the bile while most of the remainder are excreted in the urine. Also, the liver converts the potent estrogens, estradiol and estrone, into an almost impotent estrogen, estriol. Therefore, the liver plays an important role in removing those estrogens from the blood. Indeed, diminished liver function actually increases activity of estrogens in the body, sometimes causing hyperestrinism." - Guyton, p.1010 (italics are mine).
Liver toxicity today is the rule rather then the exception. Causes for liver toxicity include various toxins and other nutritional and biochemical imbalances. Let us explore what these are in more detail.
TOXINS THAT POISON THE LIVER
Toxins in the food supply. These include toxic metals, pesticide residues, preservatives and several thousand other food additives that the government allows in many prepared and processed foods. Eating only fresh, minimally processed and ideally organically grown food definitely reduces your intake of these poisons.
Some pesticides and other chemicals mimic the effects of estrogen by occupying estrogen binding sites. This makes the situation even worse. An interesting fairly recent study found that cadmium mimics the effects of estrogen (Nature, August 2003).
Thousands of organic chemicals and toxic metals in the environment. Besides food, sources of toxins include contaminated air, dental materials, especially silver amalgam fillings, and skin contact with toxins in solvents, detergents, skin care products, chlorinated and fluoridated water and other household and industrial chemicals. Building materials, carpets, plastics and office machinery also often outgas toxic chemicals.
Radiation exposure damages the liver. Everyone is exposed to some ionizing radiation from atomic bomb fallout, nuclear plant accidents, medical scans and other x-rays, dental x-rays, and other uses of radiation. All nuclear power plants emit some low-level ionizing radiation that is poisoning everyone on the planet.
Prescription drugs. This is a major cause of liver toxicity. Most all pharmaceuticals are synthetic chemicals. They all cause some liver toxicity.
contain toxic metals. For example,
thiazide diuretics contain mercury. Prozac and some popular antibiotics
such as Cipro contain fluoride, a very powerful
Vaccines are usually preserved with toxic metals such as mercury and aluminum, and often contain toxic chemicals such as benzene. One vaccine dose can give a young baby up to 20 times the permitted dose of mercury and aluminum!
According to medical studies, drug residues are present today in most, if not all municipal drinking water supplies around the world. This is a major environmental problem that has received far too little attention.
Herbs. Most herbs are somewhat toxic for the liver, as well. Used occasionally for only for a few days, they are not too harmful. However, more and more people take them them regularly because their naturopaths suggest it. They build up in the liver and damage it. This is another source of liver toxicity that few talk about.
Vitamin and mineral supplements. A few popular nutritional supplements including iron supplements, high-dose niacin, fulvic acid, humic acid, and some colloidal mineral supplements contain toxic metals that poison the liver.
MOST TOXINS REMAIN IN THE LIVER FOR DECADES
Most people and most doctors do not realize that a portion of most medical drugs and many herbs remains in oneŐs body for decades. We know this occurs because drugs that a person took years before will come out of the body during a development program.
OTHER CAUSES FOR LIVER TOXICITY
Adrenal exhaustion. This is an indirect cause. Adrenal weakness contributes to a slow oxidation rate and sluggish liver activity. Also, the body compensates for adrenal depletion by accumulating toxic oxide forms of copper, iron, chromium, selenium, manganese, aluminum, cadmium, iron, lead and other metals that are toxic to the liver. For details about this phenomenon, read The Amigos – Iron, Manganese and Aluminum.
Nutrient deficiencies. Most people are very deficient in many vital minerals and often vitamins. This seriously impairs the liver's normal detoxification pathways, resulting in liver toxicity.
Nutrient deficiencies are the result of N-P-K fertilizers used in agriculture, eating raw salads and overcooked food that does not supply enough nutrients, low quality diets of refined flour, sugar and other deficient foods, poor eating habits, stress and impaired digestion. Stress of any type increases the need for nutrients. Other articles on this website discuss all these problems such as Everyrone is Depleted And Toxic.
Autointoxication. In most people, poor digestion causes the production of toxic substances in the intestines due to fermentation and putrefaction of food. A vicious cycle occurs in which a toxic liver does not produce enough bile and digestive enzymes. Food is then poorly digested, which generates toxins that in turn worsen the condition of the liver. This further impairs enzyme production, which results in more toxins in the intestines.
This vicious cycle goes on quietly for years until one day the result is cancer or other serious illness.
Improper bowel flora such as candida albicans and other pathogenic organisms. These can produce deadly toxins in the intestines. Candida albicans, for example, produces alcohol and acetaldehyde.
Chronic infections anywhere in the body. Bacterial and other infections generate endotoxins and exotoxins. Chronic infections are much more common than imagined. We find that most people have at least a dozen low-grade chronic infections. Common sites are the teeth, eyes, ears, throat, bladder, bronchials, intestines and skin.
Stress from any cause activates the sympathetic nervous system, which in turn reduces liver activity. Stress also impairs digestion, which leads to more toxin generation in the intestines.
Autonomic nervous system imbalances, in particular excessive sympathetic nervous system activity. The sympathetic nervous system inhibits the activity of the liver. This is explained below in more detail.
Fatigue. Fatigue due to lack of sleep or other causes is an important factor in liver toxicity.
At about 12 weeks of pregnancy, the trophoblast ŇinvasionÓ of the mother slows somewhat and the placenta grows and assists the nourishing the fetus. This is called the critical period of pregnancy.
Dr. Beard found that enzymes produced by the fetal and maternal pancreas stop the growth of the trophoblast. This is the basis for the use of pancreatic enzymes in the treatment of cancer advocated by Dr. Beard, Dr. William Kelley, DDS and others (Kelley, W.D., 1997). Large quantities of pancreatic enzymes are given by mouth, which inhibit the growth of malignant cells.
This therapy works very well, is well-tolerated and would be much less costly than current cancer treatment methods. However, it is not used in medical care today. The reason is that one cannot patent pancreatic enzymes, so there is no money to be made with this therapy. We know this sounds very cold-hearted and hopefully is shocking. But it is the truth.
The pancreas plays another role. Pancreatic enzymes are needed for proper digestion. A weakened, toxic or depleted pancreas contributes to a toxic liver by failing to provide adequate enzymes for complete food digestion.
However, most people do not produce nearly enough pancreatic enzymes or they overeat, exceeding their digestive capacity. This is why we supplement everyone with pancreatic enzymes.
These pancreatic enzymes are not the same as "food enzymes" found in raw food, which do very little. Ideally, the body secretes excess pancreatic enzymes so that any cancer that begins to develop in the body is destroyed. However, very few people are in good enough health for this to occur.
Causes for deficient pancreatic activity are similar to the causes of liver toxicity. They include stress, poor-quality diets, poor eating habits, infections and toxic exposures. A complete development program will restore healthy pancreatic activity.
An important cause of impaired pancreas and liver activity is excessive activity of the sympathetic nervous system. This branch of the autonomic nervous system is sometimes referred to as the fight-or-flight response system.
Its role is to prepare the body for a stress response. However, it inhibits the activity of the liver, kidneys, pancreas, intestines and stomach. These are the organs of detoxification and the organs needed to produce digestive enzymes and cancer-fighting proteolytic enzymes (enzymes that digest foreign proteins).
Excessive activity of the sympathetic nervous system is extremely common today. Causes include stress, hurried or busy lifestyles, toxic metals, nutrient deficiencies, some toxic chemicals and negative attitudes such as fear, worry, anger, resentment and guilt. These factors keep the body in a fight-or-flight or sympathetic state most of the day.
Many cancer patients have a sympathetic dominant personality. This means they have difficulty relaxing and are often hard on themselves and others. They are often fearful, angry, guilty, perfectionistic, resentful or use other mechanisms that cause the body to remain in a sympathetic state much of the time. People who exercise too much, worry a lot, work too hard or are obsessive often overwork the sympathetic nervous system.
III. REVERSAL AND HEALING
This is a large subject. In general, any therapy that causes totipotent cells to stop becoming trophoblast will be helpful to prevent or stop the growth of cancer in the body.
For example, therapies that inhibit the sympathetic nervous system are marvelous for cancer patients. These include lots of Rest And Sleep, Red Heat Lamp Sauna Therapy, Coffee Enemas, the Pulling Down Exercise, Deep Breathing and the Development Diet. These are all part of a development program.