By Dr. Lawrence Wilson

March 2013, L.D. Wilson Consultants, Inc.


All information in this article is for educational purposes only.  It is not for the diagnosis, treatment, prescription or cure of any disease or health condition.


Definition (from Wikipedia). Acetate /ˈsɪteɪt/ is a derivative of acetic acid; that is, the salts, esters, and the polyatomic anion found in solution. Most of the approximately 5 billion kilograms of acetic acid produced annually in industry are used in the production of acetates, which usually take the form of polymers.

In nature, acetate is the most common building block for biosynthesis.  Biosynthesis means the production of proteins, vitamins, hormones, enzymes from simpler molecules.  It is a vital anabolic function or building up function of the body.

Food sources. The only food sources of preformed acetates are fats and alcohol.  Animal fats are richer in it than vegetable oils.

Acetates can be made in the body from acetic acid, which is a product of fermentation and found in substances such as vinegar.  However, this does not produce enough, in some cases, especially in fast oxidizers where the demand for acetates is higher.


Utilization.  The main way that acetates are used in the body is in the form of acetyl coenzyme-A.  This critical body chemical is involved in:

1. Energy production in the citric acid or Krebs cycle.

2. Synthesis of acetylcholine, a calming neurotransmitter.


Fast oxidizers often have a severe need for acetates.  Energy production through aerobic metabolism, also called cellular respiration, proceeds through several major metabolic transformations or pathways, or cycles.  The first is called the glycolysis cycle and the later stage is called the Krebs cycle, citric acid cycle or carboxylic acid cycle. 

According to the research of George Watson, PhD, fast oxidizers have adequately functioning glycolysis cycles, but have problems with the functioning of the carboxylic acid cycle or series of biochemical steps in the process of energy production. The problem is that in fast oxidation, one uses up their acetates too fast. They must be replaced from the diet because the body cannot produce enough of them from other chemicals in the body.

Acetates in the diet are thus extremely helpful for fast oxidizers for energy production in the citric acid cycle.  Acetates are also required to produce neurotransmitters such as acetylcholine that calm down the fast oxidation rate.  For these two reasons, at least, acetates are vital for fast oxidizers.  This is the main reason why we give more fats to fast oxidizers.


Alcoholism in fast oxidizers.  One reason for alcohol addiction in fast oxidizers is that the person is craving acetates, which are abundant in alcoholic beverages.  This is especially the case if the person is not eating much fat, which is common today.  The feeling of wellbeing derived from ingesting the acetates can be addictive, in some cases.



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